Ingredient identity record

PDRN

Polydeoxyribonucleotide — a mixture of DNA fragments, not one small molecule. That means there is no single universal molecular formula to print beside the name.

Package name: Sodium DNAAlso seen: Hydrolyzed DNASource: often salmon DNATopical evidence: Early

What the package may say

Marketing name and ingredient-list name can differ.

PDRNCommon consumer and marketing term: polydeoxyribonucleotide.

Sodium DNAAn ingredient-list name used by brands including Anua for salmon DNA-derived PDRN.

Hydrolyzed DNAAnother label used for smaller or hydrolyzed DNA material in some cosmetic products.

Salmon DNAA source description, not a standardized INCI name by itself.

Always check the complete INCI list. “PDRN” on the front label does not prove that two products use the same source, fragment size, purity or concentration.

PDRN vs c-PDRN®

The “c” is not a universal chemical grade.

TermWhat it meansWho controls it

PDRNGeneral term for polydeoxyribonucleotide DNA fragments. Products may use different sources and specifications.No single cosmetic company owns the general scientific term.

c-PDRN®A proprietary PDRN identity used for REJURAN Cosmetics and described as salmon DNA-derived material optimized with DOT® technology.PharmaResearch, South Korea. The company identifies REJURAN Cosmetics as its brand and c-PDRN®/DOT® as proprietary technology.

Important: c-PDRN® is a particular proprietary material; it should not be used as a synonym for every cosmetic PDRN. PharmaResearch did not create the general DNA polymer PDRN concept, but it developed and commercialized its own optimized c-PDRN® platform.

Evidence boundary

Injection research cannot automatically prove a serum claim.

PDRN has a longer research history in regenerative medicine. For topical cosmetics, penetration, stability, fragment size, concentration and the complete formula remain major questions. Cosmetic benefits should therefore be described cautiously as hydration, skin comfort or appearance support unless product-specific human evidence is available.

Established identityPDRN is a mixture of deoxyribonucleotide polymers.

Documented technologyPharmaResearch publicly documents its DOT® and c-PDRN® platform.

Formula-specificTopical performance cannot be transferred automatically between brands.

Do not equateCosmetic cream, medical cream and injectable products are different categories.

Sources

Why we say this

PharmaResearch officialREJURAN Cosmetics, salmon DNA-derived c-PDRN® and proprietary DOT® technology.PharmaResearch technology overviewDOT® extraction and optimization of DNA from salmon germ cells.Patent record KR20240093957AIdentifies PharmaResearch c-PDRN® and describes topical retinol/PDRN testing.Anua official product recordShows the consumer term PDRN together with the ingredient-list identity Sodium DNA.Peer-reviewed reviewPharmacological identity and clinical-use history of PDRN.

Source order: regulator or ingredient registry → patent → peer-reviewed research → manufacturer technical record → product ingredient list. Brand claims are identified as brand claims and do not become independent proof.